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September 19, 2025Deleted Journal

Evaluation of Hibiscus sabdariffa L. Extract's Antioxidant Activity and its Potential to Mitigate Chlorpyrifos-Induced Oxidative Stress in Adult Rats.

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Authors

MSM.E. SadiqMAMuhsin S. G. Al-Mozie’lAAAsia S. Abdullah

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Overview

In vivo assessment of hibiscus sabdariffa's antioxidant activity shows benefits against chlorpyrifos, indicating its potential therapeutic role.

Key Points

  • The hibiscus sabdariffa extract significantly improved antioxidant status in rats exposed to chlorpyrifos.
  • An IC50 value of 0.503 ± 0.13 indicates high antioxidant efficacy of the extract in the DPPH assay.
  • GC-MS analysis identified several active compounds in the extract, confirming its rich phytochemical content.
  • Rats treated with the extract showed reduced inflammation and normalized liver enzyme levels compared to controls.

Cite This Study

Sadiq et al. (2025) studied this question.

synapsesocial.com/papers/68d435ed713b0b5dfea75ec1https://doi.org/10.59049/2790-0231.11.2.2457
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