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September 10, 2025MoleculesOpen Access

Resveratrol as a Novel Therapeutic Approach for Diabetic Retinopathy: Molecular Mechanisms, Clinical Potential, and Future Challenges

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Authors

SKSnježana KaštelanSKSuzana KonjevodaASAna Sarić

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Overview

This review highlights resveratrol's effects on oxidative stress and inflammation in diabetic retinopathy, suggesting new treatment avenues.

Key Points

  • Resveratrol shows potential to improve early neurovascular and metabolic abnormalities in diabetic retinopathy.
  • Clinical applications of resveratrol may be hampered by poor solubility and ocular bioavailability, requiring innovative delivery methods.
  • Modulation of oxidative stress and inflammation pathways by resveratrol could transform therapeutic strategies for diabetic retinopathy.
  • Recent advances in nanoformulations may enhance the efficacy of resveratrol in diabetic retinopathy treatments.

Cite This Study

Kaštelan et al. (2025) studied this question.

synapsesocial.com/papers/68c2404eb210217d6479ac94https://doi.org/10.3390/molecules30153262
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Modulation of Oxidative Stress in Diabetic Retinopathy: Therapeutic Role of Natural Polyphenols2025 · 15 citations
  2. 2Diabetic Retinopathy in Focus: Update on Treatment Advances, Pharmaceutical Approaches, and New Technologies2025
  3. 3Breakthroughs in diabetic retinopathy diagnosis and treatment using preclinical research models: current progress and future directions2025
  4. 4Targeting microRNAs in diabetic retinopathy: from pathogenic mechanisms to therapeutic potentials2025 · 4 citations
  5. 5Recent advances in treating age-related macular degeneration and diabetic retinopathy: Current therapies and emerging novel approaches2025