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September 23, 2025Frontiers in EndocrinologyOpen Access

Targeting microRNAs in diabetic retinopathy: from pathogenic mechanisms to therapeutic potentials

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Authors

JCJiajun ChenJZJingjing ZhangCLChanglei Li

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Overview

This review discusses microRNAs' role in diabetic retinopathy, highlighting their potential as therapeutic targets and biomarkers.

Key Points

  • MicroRNAs play a critical role in diabetic retinopathy by regulating key pathological processes, including oxidative stress and inflammation.
  • Dysregulated miRNAs contribute to the pathogenesis of diabetic retinopathy, reflecting stage-specific expression patterns in patients.
  • The review suggests microRNA-based therapies, employing techniques like qRT-PCR, offer innovative strategies for managing diabetic retinopathy.
  • Targeting microRNAs may provide a non-invasive approach to diagnosing and preventing diabetic retinopathy progression.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68d44092713b0b5dfea7f1f6https://doi.org/10.3389/fendo.2025.1664604
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