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September 10, 2025International Journal of Clinical PracticeOpen Access

Triglyceride–Glucose Index as a Predictor of Chronic Kidney Injury in Primary Hypothyroidism: A Retrospective Cohort Study

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Authors

QCQianwen CaoSBShuangshan BuYXYifang Xu

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Overview

Retrospective cohort study links triglyceride–glucose index to chronic kidney injury risk, suggesting clinical significance.

Key Points

  • Higher triglyceride–glucose index correlates with increased chronic kidney injury risk in primary hypothyroidism.
  • Prevalence of chronic kidney injury was 18.06% in the studied population with significant associations identified.
  • Cox proportional hazards regression analysis indicated a notable risk increase for patients in the highest TyG quartile.
  • Significant correlations were stronger in females and patients with conditions like diabetes and hyperlipidemia.

Cite This Study

Cao et al. (2025) studied this question.

synapsesocial.com/papers/68c2404eb210217d64799e1bhttps://doi.org/10.1155/ijcp/9583252
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association Between the Triglyceride-Glucose Index and All-Cause Mortality Among Patients with Diabetes and Chronic Kidney Disease: A Retrospective Cohort Study2025
  2. 2Sex-Specific Associations Between Changes in Triglyceride–Glucose (TyG) Index and Risk of Chronic Kidney Disease: A Cohort Study of Young and Middle-Aged Adults2025 · 6 citations
  3. 3Association between the triglyceride-glucose index and major adverse cardiovascular events in patients with chronic kidney disease stages 3–42025 · 7 citations
  4. 4Triglyceride-glucose index as a marker of metabolic and inflammatory risk across different thyroid function states2026
  5. 5Comparison of triglyceride-glucose index and triglyceride-glucose related indexes in predicting cardiovascular disease incidence among populations with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study2025