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September 10, 2025Diabetes Metabolic Syndrome and ObesityOpen Access

Association Between the Triglyceride-Glucose Index and All-Cause Mortality Among Patients with Diabetes and Chronic Kidney Disease: A Retrospective Cohort Study

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Authors

MLMengjiang LiuZYZhaodan YanYZYi Zhang

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Overview

Retrospective cohort study reveals triglyceride-glucose index's link to all-cause mortality in diabetes and CKD, suggesting its potential as a predictive biomarker.

Key Points

  • Higher triglyceride-glucose index was significantly associated with increased all-cause mortality among patients with diabetes and CKD.
  • In the fully adjusted model, the triglyceride-glucose index remained an independent risk factor, with a hazard ratio of 1.582 for continuous evaluation.
  • Multivariate Cox regression and ROC curve analyses indicated the triglyceride-glucose index provided better mortality prediction compared to traditional factors.
  • The study suggests that the triglyceride-glucose index may enhance mortality risk stratification in patients with diabetes and CKD.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68c242e0b210217d647a45ffhttps://doi.org/10.2147/dmso.s539676
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1The Product of Fasting Glucose and Triglycerides As Surrogate for Identifying Insulin Resistance in Apparently Healthy Subjects2008 · 2,627 citations