Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 18, 2025NutrientsOpen Access

Sex-Specific Associations Between Changes in Triglyceride–Glucose (TyG) Index and Risk of Chronic Kidney Disease: A Cohort Study of Young and Middle-Aged Adults

View Full Paper
Ask AI
Bookmark
Share

Authors

YKYoon Ji KimYBYe Seul BaeYCYoosoo Chang

Discussion

Loading...

Member takes

Overview

Cohort study reveals higher CKD risk due to TyG index increase in men, suggesting monitoring may indicate insulin resistance.

Key Points

  • Greater increases in the TyG index significantly elevate CKD risk in men, and lower values appear protective.
  • Over 2.74 million person-years, 18,857 men and 13,394 women developed CKD, underscoring the study's extensive scope.
  • Cox proportional hazards models were applied to estimate hazard ratios for CKD risk based on TyG index changes.
  • Findings suggest monitoring TyG index trajectories could help identify high-risk young adults for early intervention.

Cite This Study

Kim et al. (2025) studied this question.

synapsesocial.com/papers/68d433a3713b0b5dfea72ed6https://doi.org/10.3390/nu17182986
View Full Paper
Ask AI
Bookmark
Share