A Risk Stratification Model for Predicting Benefits of Intensive Blood Pressure Treatment: Analysis of the Systolic Blood Pressure Intervention Trial

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Risk stratification identifies optimal candidates for intensive blood pressure treatment, suggesting improved outcomes in hypertension management.

The risk stratification model effectively identifies patients likely to benefit from intensive blood pressure treatment, enhancing personalized care.
C-indices for training and validation in the model were 0.7354 and 0.6894, respectively, demonstrating good discrimination.
Intensive blood pressure treatment significantly reduced cardiovascular event rates in the medium-risk and high-risk groups, confirming its efficacy.
No significant increase in severe adverse events was observed, indicating that the stratification approach is safe for patients.

Li et al. (2025) studied this question.

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View Full Paper

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Authors

Risk stratification identifies optimal candidates for intensive blood pressure treatment, suggesting improved outcomes in hypertension management.

The risk stratification model effectively identifies patients likely to benefit from intensive blood pressure treatment, enhancing personalized care.
C-indices for training and validation in the model were 0.7354 and 0.6894, respectively, demonstrating good discrimination.
Intensive blood pressure treatment significantly reduced cardiovascular event rates in the medium-risk and high-risk groups, confirming its efficacy.
No significant increase in severe adverse events was observed, indicating that the stratification approach is safe for patients.

Li et al. (2025) studied this question.

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