Effects of Intensive Systolic Blood Pressure Control on Kidney Outcomes in Patients With and Without CKD: A Post Hoc Analysis of SPRINT and ACCORD‐BP Trials
Post hoc analysis reveals intensive blood pressure control reduces renal failure risk in chronic kidney disease, suggesting increased risk for mild CKD progression.
Key Points
Intensive systolic blood pressure control reduced renal failure risk in chronic kidney disease participants, and increased mild progression risk.
Total participants numbered 10,946, with 2,724 classified as chronic kidney disease cases under analysis.
Cox proportional hazards models assessed risk differences in kidney outcomes between intensive and standard blood pressure control.
Results may impact treatment strategies in managing hypertensive patients with chronic kidney disease.