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June 29, 2016HypertensionOpen Access

Systolic Blood Pressure Intervention Trial (SPRINT) and Target Systolic Blood Pressure in Future Hypertension Guidelines

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Authors

BEBrent M. EganJLJiexiang LiCWC. Shaun Wagner

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Overview

Randomized trial examines blood pressure targets in treated hypertension adults, suggesting implications for future guidelines.

Key Points

  • This study aims to evaluate assumptions from the SPRINT trial regarding standard and intensive treatment effects on systolic blood pressure in adults with treated hypertension.
  • Analyzed US National Health and Nutrition Examination Survey data (2009-2012) for adults with treated hypertension.
  • Compared three groups based on age and cardiovascular risk: SPRINT-like (≥50 years), all adults (≥18 years), and those <50 years excluding SPRINT-like.
  • Measured and compared mean systolic blood pressures and treatment control percentages across groups.
  • Mean systolic blood pressures were significantly different across groups: 133.0 mm Hg, 130.1 mm Hg, and 124.6 mm Hg.
  • Higher control rates for SBP <140 mm Hg in younger age groups, with >80% in the lowest SBP group.
  • Mean SBP values for controlled subsets approached those in the intensive treatment group of SPRINT, indicating potential for similar outcomes.

Cite This Study

Egan et al. (2016) studied this question.

synapsesocial.com/papers/6a171584948575bb5a688235https://doi.org/10.1161/hypertensionaha.116.07575
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