September 10, 2025European journal of medical researchOpen Access

Early-onset colorectal cancer: a retrospective study of demographic, clinicopathological, and molecular characteristics in a single Chinese center

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Early-onset colorectal cancer presents distinct epidemiological and molecular features compared to late-onset cases.
Patients with early-onset CRC showed longer median symptom duration (90 days) than late-onset patients (60 days).
Early-onset patients were often diagnosed at advanced disease stages (24.44%), unlike their late-onset counterparts (13.45%).
Deficient mismatch repair tumors were notably more prevalent in early-onset CRC (15.90%) compared to late-onset cases (6.28%).

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Implication

Retrospective analysis reveals unique demographic and molecular features in early-onset CRC cases, indicating significant disparities with late-onset counterparts.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68c23fc3b210217d647972eb https://doi.org/10.1186/s40001-025-02819-6

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Implication

Retrospective analysis reveals unique demographic and molecular features in early-onset CRC cases, indicating significant disparities with late-onset counterparts.

Early-onset colorectal cancer: a retrospective study of demographic, clinicopathological, and molecular characteristics in a single Chinese center

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Implication

Cite This Study

Early-onset colorectal cancer: a retrospective study of demographic, clinicopathological, and molecular characteristics in a single Chinese center

Key Points

Discussion

Implication

Cite This Study

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