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September 10, 2025

Therapeutic potential of mesenchymal stem cell exosomes for tumors in the digestive system: From bench to bedside

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Authors

YLYing LiuTZTao ZhangPLPeng Lin

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Overview

Review explores MSC-exo roles in cancer therapy and highlights issues for clinical application.

Key Points

  • MSC-derived exosomes have the potential to modulate tumor microenvironments, influencing cancer progression.
  • The review emphasizes MSC-exo’s dual roles in promoting or inhibiting tumor growth, depending on context.
  • Challenges for clinical adoption of MSC-exo include production, safety, and regulatory hurdles.
  • Continued research is vital to unlock the full potential of MSC-exo in precision cancer therapy.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68c23f63b210217d64796964https://doi.org/10.36922/imo025210025
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of therapeutic potential of macrophage- or mesenchymal stem cell-derived exosomes in pancreatic cancer: An updated review2025
  2. 2From laboratory to clinic: a precise treatment strategy of mesenchymal stem cells-derived exosomes pretreated by simulating disease microenvironment2025 · 7 citations
  3. 3Molecular and therapeutic effects of mesenchymal stem cell-derived exosomes on autoimmune diseases2025 · 3 citations
  4. 4The Emerging Role of Exosome-Derived miRNAs in Cancer and Cancer Stem Cells2025
  5. 5Translational Potential of Surface Engineered Extracellular Vesicles as Theranostic Nanocarriers in Cancer Management: Recent Developments from Bench to Bedside2025 · 8 citations