September 10, 2025Scientific ReportsOpen Access

RpoB mutation patterns in Rifampicin-resistant tuberculosis: a Jiangxi Province study, 2021–2023

View Full Paper

Ask AI

Bookmark

Authors

ZMZhan Qiu Mao QZQing-Chun Zhang HZHuilie Zheng

Discussion

Member takes

Implication

Observational analysis identified mutation prevalence in the rpoB gene of Mycobacterium tuberculosis, suggesting a need for refined treatment strategies for RR-TB.

Key Points

Rifampicin resistance mutations in the rpoB gene were identified in 485 cases of TB over three years.
Children aged 5-14 years had the highest relative risk for developing Rifampicin-resistant TB, with an odds ratio of 2.68.
The study utilized tests for statistical significance and regression analysis to correlate mutation locations with resistance levels.
Findings highlight the need for precision therapy in managing RR-TB and reducing the spread of antimicrobial resistance.

Cite This Study

Mao et al. (2025) studied this question.

synapsesocial.com/papers/68c23ed7b210217d647938ff https://doi.org/10.1038/s41598-025-11949-0

View Full Paper

Ask AI

Bookmark

Implication

Observational analysis identified mutation prevalence in the rpoB gene of Mycobacterium tuberculosis, suggesting a need for refined treatment strategies for RR-TB.

RpoB mutation patterns in Rifampicin-resistant tuberculosis: a Jiangxi Province study, 2021–2023

Discussion

Member takes

Implication

Key Points

Cite This Study

RpoB mutation patterns in Rifampicin-resistant tuberculosis: a Jiangxi Province study, 2021–2023

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider