Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Tropical Journal of Natural Product ResearchOpen Access

Effect of Probiotics from Bifidobacterium infantis and Lactobacillus acidophilus on Tumour Growth Factor-Beta, Interleukin-17, and Interleukin-10 Expression in Dextran Sodium Sulfate-Induced Ulcerative Colitis Rats

View Full Paper
Ask AI
Bookmark
Share

Authors

PPPujiati PujiatiMAMohamad Hifni Aziz AndriansyahSRSeptian Arief Nur Rahman

Discussion

Loading...

Member takes

Overview

This animal study shows reduced TGF-β levels and heightened IL-10 expression in UC rats receiving probiotics, indicating a potential therapeutic role for probiotics.

Key Points

  • Treatment with probiotics significantly reduced tumour growth factor beta expression compared to the UC group.
  • Post-treatment interleukin-10 levels were higher in the UC+PROBILA group, indicating enhanced immune response.
  • Twenty-four rats were used, with separation into four groups for comparative analysis of treatments.
  • Findings support the use of probiotics, specifically B. infantis and L. acidophilus, for managing inflammation.

Cite This Study

Pujiati et al. (2025) studied this question.

synapsesocial.com/papers/68c23ed7b210217d64793832https://doi.org/10.26538/tjnpr/v9i7.19
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Breast-milk Lacticaseibacillus gasseri FN136 alleviates DSS-induced ulcerative colitis through microbiota-independent metabolite–host interactions2025
  2. 2Synergistic protective effects of β-glucan and 2025 · 5 citations
  3. 3Association of alterations in transcriptomics and intestinal immune responses with Bifidobacterium longum BAA2573 in improving dextran sulfate sodium-induced colitis2025 · 2 citations
  4. 4Assessing the beneficial effect of Lactobacillus plantarum MS1 and Lactobacillus delbrueckii YN1 on colitis in a rat model2025
  5. 5Harnessing the therapeutic potential of newly isolated Bifidobacterium adolescentis in DSS-induced colitis 44322025