Schematic Assessment of Different Mouthrinses (Chlorhexidine, Herbal, Fluoride) on Oral Microbiota Composition: A Meta-Analysis Perspective

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Discussion

Meta-analysis assesses the effects of chlorhexidine and herbal mouthrinses on oral microbiota, suggesting varied impacts.

Chlorhexidine mouthrinse may reduce pathogenic species, affecting oral microbiota diversity.
Results indicate a pooled standard mean difference (SMD) of -1.32, showing variability in mouthrinse effects.
The study included 12 randomized and observational studies assessing oral microbiota changes.
Findings highlight potential risks of microbial dysbiosis linked to chlorhexidine, indicating complexity in mouthrinse impacts.

Ahmed et al. (2025) studied this question.

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