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October 23, 2025Oral & ImplantologyOpen Access

Comparative analysis of the effect of 20% Curcumin mouthwash and 0.2% Chlorhexidine mouthwash on dental plaque and gingival inflammation: a randomized clinical trial

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Randomized clinical trial finds curcumin mouthwash comparable to chlorhexidine for dental plaque and gingival inflammation.

Improved clinical parameters observed in both curcumin and chlorhexidine mouthwash groups.
Curcumin reduced gingival bleeding index significantly compared to control, highlighting its anti-inflammatory potential.
Randomized clinical trial involved 39 participants aged 20 and older, evaluating mouthwash efficacy over 14 days.
Suggests curcumin mouthwash could be an effective adjunct therapy in periodontal disease management.

Nadafpour et al. (2025) studied this question.

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