September 17, 2025Open Access

Oral Rinse Sourced Oral Microbiota in Oral Health and Disease in a Representative U.S. Adult Population

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Discussion

Observational analysis revealed oral microbiota diversity aligns with oral health conditions, suggesting potential diagnostic uses.

Diversity and composition of oral microbiota differ significantly across various oral health conditions.
In periodontitis, a marked shift occurs towards anaerobic communities with increased microbial diversity.
Microbial features in oral rinses achieved moderate accuracy in identifying severe periodontitis using machine learning.
Key taxa affecting microbial variance were identified, indicating potential for non-invasive disease assessment.

Xie et al. (2025) studied this question.

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