September 10, 2025Journal of Neonatal SurgeryOpen Access

Development And Validation Of Stability Indicating Hptlc Method For Simultaneous Estimation Of Azithromycin, Fluconazole And Ornidazole In Combined Dosage Form

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An HPTLC method shows reliable quantification of azithromycin, fluconazole, and ornidazole, indicating a new approach to dosage form analysis.

The developed HPTLC method efficiently quantifies azithromycin, fluconazole, and ornidazole in their combined dosage forms.
Validation confirmed linear regression models for AZM, FLZ, and OZ with RF values of 0.202, 0.382, and 0.522 respectively.
The limit of detection and quantification were determined to be 0.0467 and 0.141 g/zone, ensuring accurate measurement.
Results align with ICH standards, highlighting the method’s reliability for pharmaceutical analysis.

Solat et al. (2025) studied this question.

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An HPTLC method shows reliable quantification of azithromycin, fluconazole, and ornidazole, indicating a new approach to dosage form analysis.