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September 10, 2025American Journal of Translational Research

Incidence and prognostic factors for pulmonary infection complications in elderly patients with acute myeloid leukemia

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Authors

ZNZengfeng NiLSLili ShiWJWenhua Jia

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Overview

Retrospective analysis examines pulmonary infections in elderly patients with acute myeloid leukemia, highlighting key risk factors impacting survival.

Key Points

  • The incidence of pulmonary infections in elderly AML patients was found to be 42%, significantly affecting prognosis.
  • Key risk factors for pulmonary infections include low hemoglobin, elevated CRP and procalcitonin levels, and low neutrophil and platelet counts.
  • Kaplan-Meier survival analysis revealed significantly lower median survival in patients with pulmonary infections compared to non-infected counterparts.
  • CRP and procalcitonin demonstrated the highest predictive efficacy for pulmonary infections, indicating need for improved monitoring.

Cite This Study

Ni et al. (2025) studied this question.

synapsesocial.com/papers/68c23e4fb210217d64791d2ahttps://doi.org/10.62347/kert9218
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Also Consider

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  1. 1Hematologic predictors of serious infection and impact of serious infection on long-term mortality in AML patients: Insights from propensity-matched real-world cohorts2025
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  3. 3Synergistic Effect of Antimicrobial Resistance and Cytogenetic Risk on Mortality in Acute Myeloid Leukemia2025
  4. 4Acute myeloid leukemia outcome in developing countries: a single center experience as an example in patients aged less than 60 years2025
  5. 5Uneven gains: Disparities in pneumonia-associated mortality among myeloid leukemia patients in the United States, 1999–2020 — a CDC wonder and joinpoint analysis2025