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September 10, 2025Diabetes Research and Clinical PracticeOpen Access

Adherence patterns to cardiovascular medications in people with type 2 diabetes mellitus: a retrospective cohort study using group-based trajectory analysis in primary care

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Authors

SCSri ChodapuneediJKJia Wei KohZOZhomart Orman

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Overview

Retrospective cohort study reveals adherence trajectories in primary care for people with T2DM, suggesting predictors of non-persistent behavior.

Key Points

  • Over half of individuals with T2DM displayed non-persistent adherence patterns over five years.
  • Three adherence trajectories were identified: persistent adherence (40.6%-44.3%), gradual decline (32.7%-36.6%), and early discontinuation (21.0%-26.7%).
  • Key predictors of early discontinuation include female sex, metropolitan residence, and elevated LDL cholesterol levels.
  • Intervention strategies may need to be tailored to address distinct adherence patterns among patients with T2DM.

Cite This Study

Chodapuneedi et al. (2025) studied this question.

synapsesocial.com/papers/68c241acb210217d647a05dehttps://doi.org/10.1016/j.diabres.2025.112409
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence and Predictors of Non-Adherence to Treatment in Patients with Type 2 Diabetes Mellitus2025 · 1 citations
  2. 2Partial non‐adherence to antidiabetic therapy undermines diabetes management and correlates with treatment complexity: A cross‐sectional study using blood plasma analysis2025
  3. 3Latent class growth mixture modeling of HbA1C trajectories identifies individuals at high risk of developing complications of type 2 diabetes mellitus in the UK Biobank2025 · 5 citations
  4. 42983-LB: Trajectories of Risk Factors among Participants with Long-Duration Type 1 Diabetes2026
  5. 5Characterizing treatment adherence trajectories in the <i>endTB</i> multisite cohort of drug-resistant tuberculosis patients: an application of group-based trajectory modelling2025