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September 10, 2025Jurnal Jamu IndonesiaOpen Access

Optimizing Curcumin SNEDDS via D-Optimal Design and Evaluating Wound Healing Efficacy in Wistar Rats

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FSFerdinta Daniasta Setyawan

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Overview

D-Optimal design improved curcumin solubility and efficacy in Wistar rats, suggesting enhanced wound healing potential.

Key Points

  • The optimized curcumin SNEDDS accelerated wound closure by 98% within 14 days, showcasing its therapeutic efficacy.
  • Results showed a significant encapsulation efficiency of 94.5% and a particle size of 120 nm, enhancing bioavailability.
  • The study utilized a D-Optimal design to optimize the composition of the SNEDDS for improved solubility and stability.
  • Findings highlight curcumin SNEDDS as an effective topical formulation for enhancing wound healing in animal models.

Cite This Study

Ferdinta Daniasta Setyawan (2025) studied this question.

synapsesocial.com/papers/68c23cf6b210217d6478b382https://doi.org/10.29244/jji.v10i3.393
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