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August 18, 2025PharmaciaOpen Access

Transethosome-mediated curcumin delivery promotes superior wound healing with reduced toxicity

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Authors

MRMeriem RezigueAAAlaa A. A. AljabaliWAWalhan Alshaer

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Overview

Transethosomes enhance curcumin's delivery and reduce toxicity, promoting faster healing in chronic wounds.

Key Points

  • Improved skin deposition of curcumin significantly enhances wound healing and reduces toxicity in vitro.
  • The optimized transethosome formulation had a drug loading of nearly 100% and enhanced skin penetration.
  • Assessed using in vitro models, the formulation demonstrated accelerated wound closure by 25% in 72 hours.
  • This study indicates the effectiveness of transethosomes for targeted drug delivery in wound care applications.

Cite This Study

Rezigue et al. (2025) studied this question.

synapsesocial.com/papers/68af2edecf1dd9ea359e63b6https://doi.org/10.3897/pharmacia.72.e161022
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