Impact of Pretransfusion Hemoglobin and Ferritin Levels on Growth and Clinical Parameters in Children with Transfusion-Dependent Thalassemia Major

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Growth failure is more common in adolescents with transfusion-dependent thalassemia major, and serum ferritin levels were linked to this issue.
Mean pretransfusion hemoglobin levels under 8 g/dL were prevalent in older children, showing a significant relationship with short stature.
Anthropometric measurements were taken over one year, documenting height, weight, and head circumference to assess growth patterns.
Monitoring serum ferritin is critical as elevated levels adversely affect growth in transfusion-dependent thalassemia patients.

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Cohort study shows serum ferritin correlates with growth in children, indicating higher levels may hinder progress.

Bhat et al. (2025) studied this question.

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