Endocrine Manifestations in Children and Adolescents with Thalassemia Major - A Prospective Cohort Study

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Prospective cohort study reveals high prevalence of endocrine disorders in children with thalassemia major, indicating need for regular monitoring.

Endocrine complications were found in many patients, notably glucose abnormalities and hypogonadism.
About 25% of participants had diabetes, 9.8% had hypothyroidism, and 21.6% experienced hypocalcemia.
Observational study included 51 children, assessing various endocrine parameters related to thalassemia major.
Regular monitoring is crucial for improving patient outcomes, as age and transfusion burden affect endocrinopathy risk.

Salunkhe et al. (2025) studied this question.

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Prospective cohort study reveals high prevalence of endocrine disorders in children with thalassemia major, indicating need for regular monitoring.