Correlation of insulin-like growth factor-1 and serum ferritin levels with height-for-age in transfusion-dependent thalassemia children: a cross-sectional study in limited resources setting
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Key Points
Significant correlations exist between height SDS and serum ferritin levels in thalassemia children.
The average height SDS was –2.13, with low IGF-1 levels across participants (mean: 9.2 ng/mL).
Chronic illness duration, alongside hepatomegaly, negatively correlated with height SDS in multivariate regression.
Children displayed growth issues linked to anemia and iron overload, necessitating targeted interventions.
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Implication
Cross-sectional study reveals ferritin and duration of illness are linked to height-for-age in children, indicating growth challenges in thalassemia.