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September 10, 2025Molecular BiomedicineOpen Access

Acute kidney injury: pathogenesis and therapeutic interventions

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Authors

XXXiaoqin XuTZTingting ZengSCSi Chen

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Overview

Review highlights acute kidney injury mechanisms in cancer patients, suggesting enhanced early recognition and intervention strategies.

Key Points

  • Acute kidney injury shows high morbidity and mortality, with chronic kidney disease developing as a consequence.
  • The pathogenesis involves complex metabolic disturbances and is especially relevant in cancer care.
  • Timely recognition using biomarkers and prediction models is crucial for effective intervention.
  • Understanding the molecular mechanisms is essential for developing interventions that reduce nephrotoxicity.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68c23c66b210217d64789b0dhttps://doi.org/10.1186/s43556-025-00293-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Preventing acute kidney injury and its longer-term impact in the critically ill2025
  2. 2Discovery Pipeline for AKI: Molecules, Mechanisms, Models, and Targets2025
  3. 3The evolving landscape of acute kidney injury: research directions and changes in clinical practice2026
  4. 4Transition from acute kidney injury to chronic kidney disease: molecular mechanisms and therapeutic interventions2026 · 2 citations
  5. 5The Association of Acute Kidney Injury with the Development and Progression of Chronic Kidney Disease: A Systematic Review2025