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September 10, 2025International Journal of Hygiene and Environmental HealthOpen Access

Integrated metagenomic, culture-based, and whole genome sequencing analyses of antimicrobial resistance in wastewater and drinking water treatment plants in Barcelona, Spain

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Authors

VBVictoria BallénLMLaura MondéjarYGYaiza Gabasa

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Overview

This observational analysis identifies antimicrobial resistance genes in wastewater and drinking water treatment plants in Barcelona, highlighting serious public health concerns.

Key Points

  • A total of 991 cultivable antibiotic-resistant bacteria were found, with 57.3% being multidrug-resistant.
  • The resistome was primarily composed of genes conferring resistance to beta-lactams, aminoglycosides, and macrolides.
  • Shotgun metagenomic analysis revealed high taxonomic diversity without dominant genera across treatment stages.
  • These findings underscore the role of wastewater treatment plants as hotspots for antimicrobial resistance in the environment.

Cite This Study

Ballén et al. (2025) studied this question.

synapsesocial.com/papers/68c23c20b210217d647881f3https://doi.org/10.1016/j.ijheh.2025.114664
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