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September 10, 2025Veterinary Sciences and PracticesOpen Access

Investigation of the Effects of Chrysin Against Azithromycin-Induced Heart Damage in Rats

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Authors

SASerpil AygörmezEDElif DalkılınçNANurhan Akaras

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Overview

Observational analysis revealed cardiac protection from chrysin in rats treated with azithromycin, suggesting a potential therapeutic role.

Key Points

  • Chrysin supplementation significantly reduced cardiac markers in azithromycin-treated rats, indicating a protective effect.
  • The study found that azithromycin raised oxidative stress markers and cardiac injury indicators like LDH and CK-MB.
  • Cardiac tissue analysis showed that chrysin improved antioxidant enzyme activities, reversing oxidative stress caused by azithromycin.
  • Findings suggest that chrysin, a natural flavonoid, may help mitigate heart damage resulting from antibiotic treatment.

Cite This Study

Aygörmez et al. (2025) studied this question.

synapsesocial.com/papers/68c23bd7b210217d647872b5https://doi.org/10.17094/vetsci.1675127
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