September 10, 2025Journal of applied science and environmental managementOpen Access

Phytochemical, Acute Oral Toxicity, and In-Vitro Anti-Diabetic Activity Screening of the Methanol Leaf Extract of Landolphia owariensis (Apocynaceae)

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Authors

OEOsayemwenre ErharuyiUniversity of Benin AAA. L. AkeleUniversity of Benin

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Implication

This research investigates acute oral toxicity and anti-diabetic activity in Landolphia owariensis, suggesting both potential and risks of the extract.

Key Points

The methanol leaf extract of Landolphia owariensis demonstrated mild-moderate α-amylase inhibitory activity.
Acute toxicity testing indicated the extract has an LD50 of 3808 mg/kg body weight, revealing its toxic potential.
Phytochemical analysis identified key compounds such as saponins and alkaloids, while tannins were absent.
Therapeutic use may be limited due to the extract's potential toxicity if consumed in high doses.

Cite This Study

Erharuyi et al. (2025) studied this question.

synapsesocial.com/papers/68c23b8fb210217d64785f0b https://doi.org/10.4314/jasem.v29i7.3

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Implication

This research investigates acute oral toxicity and anti-diabetic activity in Landolphia owariensis, suggesting both potential and risks of the extract.

Phytochemical, Acute Oral Toxicity, and In-Vitro Anti-Diabetic Activity Screening of the Methanol Leaf Extract of Landolphia owariensis (Apocynaceae)

Discussion

Member takes

Implication

Key Points

Cite This Study

Phytochemical, Acute Oral Toxicity, and In-Vitro Anti-Diabetic Activity Screening of the Methanol Leaf Extract of Landolphia owariensis (Apocynaceae)

Discussion

Member takes

Implication

Key Points

Cite This Study

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