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September 10, 2025International Journal of Clinical PracticeOpen Access

A Meta‐Analysis on the Effect of Vitamin D Supplementation on Endothelial Function in Adults

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Authors

VMVali MusazadehMMMahsa MahmoudinezhadPPPedram Pam

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Overview

Meta-analysis assesses vitamin D's effect on endothelial function in adults, indicating varying outcomes based on underlying conditions.

Key Points

  • No significant changes in endothelial function were observed after vitamin D administration.
  • Subgroup analysis indicated that patients with chronic kidney disease saw improvement in pulse wave velocity.
  • The analysis incorporated data from 31 randomized controlled trials with a total of 3252 participants.
  • Heterogeneity in study designs and patient characteristics may affect the overall findings.

Cite This Study

Musazadeh et al. (2025) studied this question.

synapsesocial.com/papers/68c23b4ab210217d64784bfbhttps://doi.org/10.1155/ijcp/3788298
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Vitamin E Supplementation on Biomarkers of Endothelial Function in Adults: A GRADE-assessed Systematic Review and Dose-Response Meta-Analysis2026
  2. 2Effect of vitamin D supplementation for major adverse cardiovascular events: A meta-analysis based on randomized controlled trials2025
  3. 3Effect of vitamin D supplementation on body composition, lipid profile, and glycemic indices in patients with obesity-associated metabolic syndrome: a systematic review and meta-analysis2025
  4. 4Effectiveness of Vitamin D Supplementation on Biochemical, Clinical, and Inflammatory Parameters in Patients with Different Types of Diabetes: A Systematic Review and Meta-Analysis2025 · 8 citations
  5. 5Effect of Vitamin D2 Supplementation on 25-Hydroxyvitamin D3 Status: A Systematic Review and Meta-Analysis of Randomized Controlled Trials2025