September 10, 2025Open Access

Figure S14 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

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Discussion

Pharmacological modulation of ppar-δ affects invasion and metastasis in pancreatic cancer models, highlighting its role.

Pharmacological modulation of ppar-δ inhibits metastasis in pancreatic cancer, indicating its pivotal role.
Meta-analysis showed enhanced invasion and metastasis in vivo, with the highly metastatic PDX CTCA model.
Research utilized advanced techniques in pharmacological modulation to study ppar-δ effects on tumor behavior.
Findings suggest targeting ppar-δ may offer new therapeutic avenues for pancreatic cancer management.

Parejo-Alonso et al. (2025) studied this question.

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