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September 5, 2025Oncology and Translational MedicineOpen Access

Enhancing chemosensitivity in pancreatic cancer: novel strategies to overcome therapeutic resistance

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Authors

WLWenhao LuoMZMenggang ZhangHCHao Chen

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Overview

Review explores innovative strategies to boost chemosensitivity and combat chemoresistance in pancreatic cancer, emphasizing targeted therapies and immunotherapy.

Key Points

  • Addressing chemoresistance is crucial for improving clinical outcomes in pancreatic cancer patients.
  • Current therapies, including chemotherapy, often fail due to the adaptive mechanisms of tumor cells.
  • Innovative strategies are needed to enhance chemosensitivity and improve patient survival rates.
  • Pancreatic ductal adenocarcinoma remains a significant challenge, with limited effective treatment options.

Cite This Study

Luo et al. (2025) studied this question.

synapsesocial.com/papers/68c239a3b210217d6477c8d8https://doi.org/10.1097/ot9.0000000000000098
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Overcoming therapy resistance in pancreatic cancer: challenges and emerging strategies2025
  2. 2Nanomedicine Breakthroughs Overcoming Pancreatic Cancer Drug Resistance through Precision Nano-Interventions2025
  3. 3Remodeling the pancreatic tumor microenvironment by chemotherapy: New opportunities for combination therapy.2026
  4. 4Advances in pancreatic cancer early diagnosis, prevention, and treatment: The past, the present, and the future2025
  5. 5Mechanisms of cancer cell rescue against pancreatic cancer therapeutics: Intrinsic and acquired resistance2025