Adverse Drug Reactions due to Antitubercular Therapy in Multidrug-Resistant Tuberculosis in Meghalaya, India

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Discussion

Observational study identifies adverse drug reactions in MDR-TB therapy, suggesting improvements needed for patient compliance.

The study found that 54 adverse drug reactions were reported among MDR-TB patients, highlighting ongoing treatment challenges.
ADRs primarily affected the gastrointestinal tract, with vomiting and nausea accounting for 33% of cases identified.
Most ADRs were classified as mild-level 1, with 65% marked as possible, necessitating careful monitoring and management.
Nearly 43% of patients experienced serious ADRs requiring changes in medication, emphasizing the need for proactive management.

Sarkar et al. (2025) studied this question.

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