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September 5, 2025Tropical Journal of Natural Product ResearchOpen Access

Effects of the Aqueous Extract of Zingiber officinale Rhizomes and a Combination of Vernonia amygdalina and Ocimum gratissimum leaves on the Fasting Blood Glucose and Lipid Profile Levels of Alloxan-Induced Diabetic Rats

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Authors

OOOmonkhelin J OwolabiAAAbigail M. AkhigbemenIBIsrael O. Bolanle

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Overview

Experiment shows that herbal extracts significantly improve fasting blood glucose and lipid profiles in alloxan-induced diabetic rats, suggesting potential therapeutic benefits.

Key Points

  • Aqueous extract of zingiber officinale significantly reduced fasting blood glucose levels in diabetic rats, indicating antidiabetic potential.
  • The combination of vernonia amygdalina and ocimum gratissimum significantly improved lipid profiles compared to untreated diabetics, showing beneficial effects.
  • Treatment involving both plant extracts was administered over 14 days, evaluating their combined impact on glucose and lipid metabolism.
  • Findings highlight the usefulness of traditional herbal remedies in managing diabetes mellitus and hyperlipidaemia.

Cite This Study

Owolabi et al. (2025) studied this question.

synapsesocial.com/papers/68c23966b210217d6477be7fhttps://doi.org/10.26538/tjnpr/v9i8.69
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Also Consider

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  1. 1Synergistic Effect of Combined Leaf Extract of Vernonia amygdalina, Ocimum gratissimum, and Zingiber officinale Tuber on Phytochemical Profile, Antioxidant Activity, Serum Insulin, and Biochemical Parameters in Streptozotocin-Induced Diabetic Rats2025
  2. 2Effect of combined extract of leaves of Medicago sativum and seeds of Garcinia kola on biochemical indices of alloxan-induced diabetic rats.2025
  3. 3Antidiabetic potential of <i>Celtis tetrandra</i> Roxb. leaf extracts in alloxan-induced diabetic rats, lipid profile, and histopathological analysis of pancreas2025
  4. 4THE EFFECT OF SOME ACTIVE COMPOUNDS OF THE AQUEOUS EXTRACT OF BASIL ON SOME BIOCHEMICAL PARAMETERS OF MALE RATS INDUCED WITH DIABETES2025
  5. 5Antidiabetic assessment of mango and soursop leaves bioactive phytochemical formulation on streptozotocin-induced rat model2025