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September 5, 2025Open Access

Phenotypic Antibacterial Resistance Profiles of Azadirachta indica and Calotropis procera Fresh Leaf Extracts Against Multidrug-Resistant Pathogens

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Authors

HLHajara LabaranHAHabiba Usman AliyuSISani M. Isyaka

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Overview

This research demonstrates antibacterial activity against multidrug-resistant strains using plant extracts, suggesting promising alternatives to conventional antibiotics.

Key Points

  • The extracts of A. indica and C. procera effectively inhibited multidrug-resistant bacteria, particularly P. aeruginosa.
  • Testing revealed significant variation in inhibition zones, indicating diverse antibacterial properties linked to bioactive compounds.
  • Analysis included agar disc diffusion and minimum inhibitory concentration assays to assess the resistance profiles of the extracts.
  • The findings suggest these plant extracts may serve as natural alternatives to traditional antibiotics, especially against resistant strains.

Cite This Study

Labaran et al. (2025) studied this question.

synapsesocial.com/papers/68c23965b210217d6477b8b3https://doi.org/10.70389/pjpb.100019
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ANTIBACTERIAL ACTIVITY AND RESISTANCE PROFILES OF AZADIRACHTA INDICA AND CALOTROPIS PROCERA ALONGSIDE MULTIDRUG-RESISTANT BACTERIA2025
  2. 2Phytochemical Profile and Antioxidant Activity of Ethanolic Extracts from Selected Wild Medicinal Plants: Azadirachta indica, Acalypha indica, and Muntingia malabura2025
  3. 3ANTIOXIDANT AND PHYTOCHEMICAL PROPERTY OF AZADIRACHTA INDICA AND CALOTROPIS PROCERA: CURATIVE INSIGHTS FOR OXIDATIVE STRESS-RELATED AILMENTS2025
  4. 4Synergistic Antibacterial Effects of Leaf Extracts of Acacia nilotica and Psidium guajava against Extended Spectrum Beta Lactamase (ESBL) Producing E. coli and Klebsiella pneumoniae2024
  5. 5Chemical Characterization and Evaluation of the Antimicrobial Properties of Leaf Extracts from Five Ethnomedicinal Plants in Paschim Medinipur District, West Bengal, India2025