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September 10, 2025

Synergistic Antibacterial Effects of Leaf Extracts of Acacia nilotica and Psidium guajava against Extended Spectrum Beta Lactamase (ESBL) Producing E. coli and Klebsiella pneumoniae

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Authors

SASalawudeen AdamuMAMansur AbdulrasheedHIH. I. Ibrahim

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Overview

Research reveals combined antibacterial effects of plant extracts against E. coli and K. pneumoniae, suggesting potential for new antimicrobial treatments.

Key Points

  • Methanol extracts of Acacia nilotica and Psidium guajava showed the highest antibacterial activity.
  • The minimum inhibitory concentration (MIC) was found to be 2.5% and 5% for the plant extracts.
  • Combined extracts were tested using agar well diffusion technique and showed significant synergistic effects.
  • Findings indicate potential for developing new natural antimicrobial drugs targeting ESBL-producing pathogens.

Cite This Study

Adamu et al. (2024) studied this question.

synapsesocial.com/papers/68c2443bb210217d647aa5cfhttps://doi.org/10.64290/bima.v8i2b.708
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