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January 30, 2025

Antibacterial Activity and Resistance Profiles of Azadirachta Indica and Calotropis Procera Alongside Multidrug-Resistant Bacteria

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Authors

HLHajara LabaranUniversity of NigeriaHUHadiza Abdullahi UsmanFederal University KashereSISani M. IsyakaObong University

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Implication

Observational analysis shows significant antibacterial activity against multidrug-resistant bacteria, highlighting potential therapeutic applications.

Key Points

  • C. procera showed substantial antibacterial activity, particularly against P. mirabilis and K. pneumoniae, indicating its therapeutic promise.
  • Methanol extracts from both plants demonstrated effective bactericidal activity, with A. indica notably effective against P. mirabilis and S. enterica.
  • Genotypic analysis revealed resistance genes, including blaNDM-1, blaSHV, and blaTEM, in certain multidrug-resistant strains, raising public health concerns.
  • Preliminary findings support further clinical studies to validate the use of these plants as antibacterial agents against resistant pathogens.

Cite This Study

Labaran et al. (2025) studied this question.

synapsesocial.com/papers/68af2979cf1dd9ea359e31e7https://doi.org/10.64290/jsls.v1i1.24
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phenotypic Antibacterial Resistance Profiles of Azadirachta indica and Calotropis procera Fresh Leaf Extracts Against Multidrug-Resistant Pathogens2025
  2. 2ANTIOXIDANT AND PHYTOCHEMICAL PROPERTY OF AZADIRACHTA INDICA AND CALOTROPIS PROCERA: CURATIVE INSIGHTS FOR OXIDATIVE STRESS-RELATED AILMENTS2025
  3. 3Phytochemical-Antibiotic Synergy: Exploring the Antibacterial Potential of Calotropis procera in Combination Therapy2025 · 1 citations
  4. 4Antimicrobial activity of Azadirachta indica and Moringa oleifera extracts against some pathogenic bacteria isolated from urinary tract infections2025
  5. 5Phytochemical Profile and Antioxidant Activity of Ethanolic Extracts from Selected Wild Medicinal Plants: Azadirachta indica, Acalypha indica, and Muntingia malabura2025