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September 5, 2025Advances in UrologyOpen Access

Time to Prostate‐Specific Antigen Failure as a Unique Prognosticator of Overall Survival in Biochemically Recurrent Prostate Cancer Patients Undergoing Radical Prostatectomy

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Authors

TSTomoyuki ShimabukuroTTT TokunagaKSKosuke Shimizu

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Overview

Long-term analysis uncovers time to biochemical recurrence as a key survival indicator in biochemically recurrent prostate cancer patients, highlighting its clinical significance.

Key Points

  • Time to biochemical recurrence was identified as a significant independent prognostic factor for overall survival.
  • In a cohort of 152 patients with recurrent prostate cancer, 21 all-cause deaths were recorded over a median follow-up of 118 months.
  • A TTBR cutoff of 12 months significantly impacts overall survival rates among biochemically recurrent prostate cancer patients.
  • Patients with a TTBR of ≤ 12 months experienced markedly worse outcomes, supporting clinical monitoring strategies.

Cite This Study

Shimabukuro et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d6477ab69https://doi.org/10.1155/aiu/2961319
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  1. 1Prognostic Factors Associated with Biochemical Relapse After Radiotherapy in Localized Prostate Cancer: A Retrospective Cohort Study2025
  2. 2Prognostic Factors Associated with Biochemical Relapse after Radiotherapy in Localized Prostate Cancer: A Retrospective Cohort Study2025
  3. 3Incidence, Risk Factors, and Clinical Characteristics of Late Biochemical Recurrence Following Robot‐Assisted Radical Prostatectomy2025
  4. 4Prognostic Impact of Time to Castration Resistance on Overall Survival in Patients With Metastatic Castration‐Sensitive Prostate Cancer2025
  5. 5Prognostic Significance of <i>RB1</i> Alterations on Outcomes in Metastatic Prostate Cancer2025