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September 5, 2025Italian Journal of MedicineOpen Access

P15 | Heart failure with reduced ejection fraction (HFrEF) and iron deficiency

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Overview

Data review shows significant impact of iron deficiency on HFrEF patients, suggesting further treatment is needed.

Key Points

  • Iron deficiency significantly affects patients with heart failure with reduced ejection fraction (HFrEF), with 39.4% having ferritin levels <100 μg/L.
  • Patients treated with ferric carboxymaltose improved their hemoglobin levels by at least 0.8 g/dL before discharge, indicating effective treatment.
  • A total of 97% of patients reported dyspnea upon admission, but this dropped to 8.4% post-treatment, demonstrating symptom improvement.
  • CKD and other comorbidities were prevalent in the patient group, underlining the need for comprehensive management in HFrEF cases.

Cite This Study

A 2025 study studied this question.

synapsesocial.com/papers/68c238d2b210217d64779db1https://doi.org/10.4081/itjm.2025.2211
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Iron Deficiency and Anemia in Heart Failure2025
  2. 2Effects of Iron Deficiency Anemia on Functional Status of Patients of Heart Failure with Reduced Ejection Fraction2026
  3. 3Iron deficiency in primary care patients with heart failure: a cross-sectional study of the heart failure in Southern Sweden (HISS) cohort2026
  4. 4Iron supplementation in heart failure and iron deficiency: does it help?2025 · 4 citations
  5. 5Iron Deficiency Screening in Patients Admitted with Acute Heart Failure Decompensation2026