Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 23, 2025Global CardiologyOpen Access

Iron supplementation in heart failure and iron deficiency: does it help?

View Full Paper
Ask AI
Bookmark
Share

Authors

LKLaibah Arshad KhanSJSyed Sarmad JavaidJBJaved Butler

Discussion

Loading...

Member takes

Overview

Randomized controlled trials show IV iron improves functional outcomes in heart failure patients, suggesting clinical benefits in managing iron deficiency.

Key Points

  • IV iron therapy significantly improves functional outcomes in heart failure patients with iron deficiency.
  • In trials like FAIR-HF, 50% of patients showed NYHA class improvement compared to 30% with placebo.
  • Despite some variability, IV iron reduces heart failure hospitalizations, indicating potential for better management.
  • Meta-analysis results indicate consistent long-term benefits of IV iron in reducing composite cardiovascular outcomes.

Cite This Study

Khan et al. (2025) studied this question.

synapsesocial.com/papers/68d440ac713b0b5dfea803c7https://doi.org/10.4081/cardio.2025.82
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Intravenous Iron in Heart Failure Patients With Iron Deficiency: A Meta-Analysis of Randomized Controlled Trials.2025
  2. 2Comparative Effectiveness and Safety of Intravenous Versus Oral Iron Therapy With Iron-Deficient Heart Failure: A Network Meta-Analysis of Randomized Controlled Trials2025 · 1 citations
  3. 3Iron Deficiency and Anemia in Heart Failure2025
  4. 4Intravenous ferric carboxymaltose in heart failure with iron deficiency (<scp>FAIR</scp>‐<scp>HF2 DZHK05</scp> trial): Sex‐specific outcomes2025 · 6 citations
  5. 5Real-World Review of Adherence to Guideline-Directed Intravenous Iron Therapy in Heart Failure Patients: A Retrospective Observational Study from a Tertiary Care Hospital in Oman2025