September 5, 2025Terapevticheskii arkhivOpen Access

Clinical and morphological features and functional parameters in patients with gastroesophageal reflux disease and Barrett's esophagus

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Observational analysis finds decreased esophageal motility in patients with Barrett's esophagus, indicating higher reflux severity.

Patients with GERD and Barrett's esophagus show significantly higher instances of intense heartburn and swallowing difficulties.
Lower esophageal sphincter pressure was notably lower in patients with Barrett's esophagus (15.1 mmHg) compared to those without (20.3 mmHg).
Esophageal motility was less effective in patients with Barrett's esophagus, linked to a substantial decrease in distal contractile integral.
Patients with Barrett's esophagus also experienced more acidic reflux and longer pH exposure times compared to those without.

Трухманов et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark