September 5, 2025Neurocritical CareOpen Access

SAHRANG: Subarachnoid Hemorrhage Recovery and Galantamine: A Pilot Multicenter Randomized Placebo-Controlled Trial

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Discussion

Multicenter trial shows galantamine's tolerability is similar to placebo in subarachnoid hemorrhage patients, indicating safety.

Galantamine was tolerable and safe compared to placebo in patients post subarachnoid hemorrhage.
No significant differences were found in adverse events or mortality rates between the groups at 90 days.
This multicenter, double-masked trial involved 60 adult patients with aneurysmal subarachnoid hemorrhage.
These findings suggest that galantamine might not worsen outcomes in subarachnoid hemorrhage patients.

Yang et al. (2025) studied this question.

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