Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
August 17, 2025Research Journal of Pharmacy and Technology

Development of Mesalamine Self Nanoemulsifying Drug Delivery System to Improve Solubility and Permeability

View Full Paper
Ask AI
Bookmark
Share

Authors

ASAnilkumar J. ShindeRMRohan R. MiraseFTFiroj A. Tamboli

Discussion

Loading...

Member takes

Overview

Formulated self-nanoemulsifying drug delivery system improved solubility and permeability of mesalamine, indicating enhanced efficacy.

Key Points

  • The optimized self-nanoemulsifying drug delivery system significantly improved mesalamine's solubility and permeability.
  • Solid SNEDDS achieved a mean globule size of 107 nm and a zeta potential of -17 mV, confirming its stability.
  • Preparation involved a pseudoternary phase diagram and Box-Behnken experimental design to optimize the formulation.
  • Enhanced drug release in vitro suggests improved therapeutic efficacy for mesalamine treatment.

Cite This Study

Shinde et al. (2025) studied this question.

synapsesocial.com/papers/68c23652b210217d64774258https://doi.org/10.52711/0974-360x.2025.00464
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Advances in Self-Nanoemulsifying Drug Delivery Systems: Mechanistic Insights and Formulation Strategies2025 · 6 citations
  2. 2Formulation Development and In-Vitro Characterization of Liquid and Solid Self Microemulsifying Drug Delivery System of Apremilast2025
  3. 3Advancements and Innovations in Herbal and non-herbal, Self-Micro emulsifying Drug Delivery Systems (SMEDDS): A Comprehensive Review2025 · 1 citations
  4. 4Comparative Study of Snedds and Sedds for Enhancing Oral Delivery of Vildagliptin2025 · 2 citations
  5. 5Revolutionizing Drug Delivery: The Promise of Self-emulsifying Systems in Overcoming Bioavailability Challenges2025