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August 16, 2025American Journal of Cancer Research

Clinical impact and safety of continuous renal replacement therapy in critically ill patients with solid tumors and acute kidney injury: a retrospective cohort analysis

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Authors

TLTing LuoFLFei LinHHHengcan Huang

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Overview

Retrospective cohort analysis demonstrates improved AKI remission and survival in ICU patients, suggesting CRRT is effective and safe.

Key Points

  • CRRT significantly improved AKI remission and metabolic parameters, leading to better outcomes in patients with solid tumors and acute kidney injury.
  • After propensity score matching, the CRRT group showed higher 90-day survival rates at 47.52% compared to 39.01% in the non-CRRT group.
  • Analyses using XGBoost machine learning yielded AUCs of 0.78 for mortality prediction and 0.75 for AKI remission.
  • The findings support the use of CRRT in this high-risk population, indicating it provides effective renal recovery with an acceptable safety profile.

Cite This Study

Luo et al. (2025) studied this question.

synapsesocial.com/papers/68c23626b210217d64773bd4https://doi.org/10.62347/votk4097
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Markers Predicting Mortality in Patients Receiving Renal Replacement Therapy in the Intensive Care Unit: A One-Year Retrospective Study2025
  2. 2Evaluation of Outcomes After Early Versus Late Initiation of Continuous Renal Replacement Therapy in Adult Patients With Sepsis-Associated Acute Kidney Injury2026
  3. 3Impact of Early Initiation of Renal Replacement Therapy on Renal Recovery and Mortality in Critically Ill Patients with Acute Kidney Injury: A Prospective Cohort Study2025 · 3 citations
  4. 4Risk stratification for in-hospital mortality in sepsis-associated acute kidney injury patients receiving continuous renal replacement therapy: an interpretable, externally validated machine learning study2026
  5. 5Prognosis of critically ill patients with cirrhosis and acute kidney injury initiated on dialysis2026