August 15, 2025MicroorganismsOpen Access

Genomic Epidemiology of ESBL- and Carbapenemase-Producing Enterobacterales in a Spanish Hospital: Exploring the Clinical–Environmental Interface

View Full Paper

Ask AI

Bookmark

Authors

SMSandra Martínez-ÁlvarezUniversidad de La Rioja MAMaría Ángeles Asencio-EgeaHospital General San Juan de Dios MVMaría Huertas VaqueroHospital General Universitario de Ciudad Real

Discussion

Member takes

Implication

Genomic analysis reveals links between clinical and environmental resistance patterns in Escherichia coli and Klebsiella pneumoniae isolates, suggesting a One Health approach to combatting antimicrobial resistance.

Key Points

High-risk clones of ESBL- and CP-producing Escherichia coli and Klebsiella pneumoniae were found in clinical and environmental settings, highlighting the persistence of antimicrobial resistance.
Genomic analysis identified blaCTX-M-15 as the most prevalent gene in ESBL-producing E.coli, impacting treatment options and patient safety.
The study employed whole-genome sequencing to elucidate phylogenetic relationships, identifying close links between human and environmental strains.
Findings indicate the critical role of surveillance in understanding the spread of antimicrobial resistance across health and ecological systems.

Cite This Study

Martínez-Álvarez et al. (2025) studied this question.

synapsesocial.com/papers/68c235ccb210217d64772549 https://doi.org/10.3390/microorganisms13081854

View Full Paper

Ask AI

Bookmark

Genomic Epidemiology of ESBL- and Carbapenemase-Producing Enterobacterales in a Spanish Hospital: Exploring the Clinical–Environmental Interface

Discussion

Member takes

Implication

Key Points

Cite This Study

Genomic Epidemiology of ESBL- and Carbapenemase-Producing Enterobacterales in a Spanish Hospital: Exploring the Clinical–Environmental Interface

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider