August 12, 2025CephalalgiaOpen Access

Plasma adrenomedullin levels in migraine: A registry for migraine (REFORM) study

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Authors

RDRogelio Domínguez-MorenoUniversity of Copenhagen WKWilliam Kristian Karlsson HAHaidar M. Al‐KhazaliUniversity of Copenhagen

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Implication

Observational analysis found no significant difference in plasma adrenomedullin levels in migraine patients, suggesting potential biomarker exploration for migraine variations.

Key Points

Plasma adrenomedullin levels showed no significant difference between migraine participants and healthy controls, indicating a need for further research.
Episodic migraine sufferers had lower plasma adrenomedullin levels compared to healthy controls, highlighting a potential variation in biomarkers.
The study involved 667 migraine patients and 147 healthy controls over two years, using a validated assay to quantify levels.
The findings suggest exploring other potential blood-based biomarkers for migraine may be beneficial for future investigations.

Cite This Study

Domínguez-Moreno et al. (2025) studied this question.

synapsesocial.com/papers/68c23595b210217d647713b3 https://doi.org/10.1177/03331024251360234

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Implication

Observational analysis found no significant difference in plasma adrenomedullin levels in migraine patients, suggesting potential biomarker exploration for migraine variations.

Plasma adrenomedullin levels in migraine: A registry for migraine (REFORM) study

Discussion

Member takes

Implication

Key Points

Cite This Study

Plasma adrenomedullin levels in migraine: A registry for migraine (REFORM) study

Discussion

Member takes

Implication

Key Points

Cite This Study

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