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August 25, 2025Journal of Clinical MedicineOpen Access

Factors Involved in the Progression of Preclinical Atherosclerosis in People with Type 1 Diabetes

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Authors

CVClara ViñalsICIgnacio CongetMGMontse Granados

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Overview

Prospective analysis reveals worsening preclinical atherosclerosis in type 1 diabetes, suggesting the need for improved prevention strategies.

Key Points

  • Atherosclerosis progression occurs in 40.4% of individuals with type 1 diabetes over a 5-year follow-up period, despite improved cardiovascular risk factor control.
  • Older age is associated with 38% increased risk of atherosclerosis progression, while active smoking raises the risk threefold.
  • Logistic regression identified Steno Type 1 Risk Engine as a significant predictor of atherosclerosis progression after controlling for other cardiovascular risk factors.
  • Identifying individuals at highest risk using ST1RE may enable targeted preventive strategies in type 1 diabetes patients.

Cite This Study

Viñals et al. (2025) studied this question.

synapsesocial.com/papers/68af7df87567bf4f94ff4fb9https://doi.org/10.3390/jcm14176004
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Preclinical carotid atherosclerosis is independently associated with cardiovascular events and mortality in type 1 diabetes2026
  2. 2Predicting subclinical atherosclerosis in adults with type 1 diabetes using cardiovascular risk models: a cross‑sectional study from Italy2026
  3. 3Risk and protective factors for coronary atherosclerosis and myocardial dysfunction in individuals with long-duration type 1 diabetes2025
  4. 4Adherence to Modified American Heart Association Cardiovascular Health Standards Is Associated With Lower Atherosclerotic Burden in Mediterranean Individuals With Type 1 Diabetes2025
  5. 5Risk Stratification and Coronary Optical Coherence Tomography Findings in Asymptomatic Patients With Type 1 Diabetes Mellitus2025