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August 19, 2025Cancer CommunicationsOpen Access

Lactylation in cancer biology: Unlocking new avenues for research and therapy

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Authors

XHXiaoyu HouZHZhenya HongHZHuimin Zen

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Overview

This review demonstrates lactylation's impact on tumor microenvironments and metabolic reprogramming, highlighting its potential as a therapeutic target.

Key Points

  • Lactylation plays a crucial role in cancer progression by influencing metabolic reprogramming and immune evasion.
  • Research indicates that lactylation contributes significantly to the adaptation of tumor cells to nutrient-deprived environments.
  • The review explores targeting lactylation as a promising approach to improve cancer therapy outcomes against therapy resistance.
  • Understanding lactylation helps in uncovering novel strategies for cancer treatment and its integration into clinical practice.

Cite This Study

Hou et al. (2025) studied this question.

synapsesocial.com/papers/68af751a7567bf4f94fee3d3https://doi.org/10.1002/cac2.70054
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lactylation in Cancer: Advances, Challenges, and Future Perspectives.2025
  2. 2Effects of lactylation on the hallmarks of cancer (Review)2025
  3. 3Insights into recent findings and therapeutic potential of nonhistone lactylation in cancer2025
  4. 4Nonhistone lactylation: A hub for tumour metabolic reprogramming and epigenetic regulation2025
  5. 5Targeting Lactylation: From Metabolic Reprogramming to Precision Therapeutics in Liver Diseases2025