Network Pharmacology and In Vitro Validation of Brazilin as a Potential Apoptosis-Inducing Agent in HBV-Related Hepatocellular Carcinoma

View Full Paper

Ask AI

Bookmark

Brazilin significantly induced apoptosis in Hep3B cells, indicating its potential as an apoptosis-inducing agent.
The cytotoxicity of brazilin was evaluated with an IC50 value of 17 µM after 72 hours of treatment.
Utilizing network pharmacology, key gene targets such as SRC and EGFR were identified for brazilin's action.
These results highlight the potential of brazilin to treat HBV-related hepatocellular carcinoma while providing liver protection.

Discussion

No takes yet. Share an insight, caveat, or question.

Network pharmacology reveals brazilin's anticancer potential in hepatocellular carcinoma, suggesting new therapy for HBV-related cases.

Hanifa et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark