August 20, 2025Spine

Current use and Complications Associated with Bone Morphogenetic Protein in Spine Fusion Surgery

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Patients with rhBMP-2 showed no significant trend in complications, despite extensive use in surgeries.
In total, 9809 patients were reviewed, highlighting the varying rates of rhBMP-2 application across different spine surgeries.
Spine fusion procedures revealed higher complication rates associated with rhBMP-2 use in patients with pre-existing risk factors.
Long fusions with rhBMP-2 were linked to a higher prevalence of osteoporosis compared to short fusions without it.

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Retrospective analysis of rhBMP-2 and non-rhBMP-2 in spine fusion, revealing varying complication rates among different procedures.

Korsun et al. (2025) studied this question.

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