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August 17, 2025CureusOpen Access

Association of D-dimer Levels in Acute Ischaemic Stroke Patients at Tertiary Care Centre in Northern India: A Prospective Observational Study

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Authors

VAVirendra AtamMJManohar K JhaNGNikhil Gupta

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Overview

Observational study shows elevated D-dimer levels are linked to severity and in-hospital outcomes in stroke patients, indicating its prognostic value.

Key Points

  • Elevated d-dimer levels indicate worse in-hospital outcomes and greater stroke severity among patients with acute ischemic stroke.
  • Mean d-dimer levels varied significantly across stroke severities: mild at 46.30 mcg/dL and severe at 195.84 mcg/dL, reflecting a strong correlation with NIHSS scores.
  • Prospective observational study conducted with 120 acute ischemic stroke patients over one year assessed using the NIHSS and modified Rankin Scale for outcomes.
  • Findings emphasize the potential use of d-dimer as a key prognostic biomarker for risk stratification in acute ischemic stroke patients.

Cite This Study

Atam et al. (2025) studied this question.

synapsesocial.com/papers/68af3e49cf1dd9ea359eb6d3https://doi.org/10.7759/cureus.90313
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Stratifying Neurological Severity in Acute Ischemic Stroke: The Independent and Combined Prognostic Value of Admission D-Dimer and High-Sensitivity C-Reactive Protein2025
  2. 2Inverse Association Between D-Dimer Levels and Glasgow Coma Scale Scores in Hemorrhagic Stroke Patients: A Cross-Sectional Study2025
  3. 3Elevated d-dimer predicts worse outcomes in hospitalized adults with sickle cell crisis: A real-world multicenter study2025
  4. 4D-dimer Levels as a Prognostic Inpatient Mortality Indicator in COVID-19 Patients: Insights from a Cross-Sectional Study2025
  5. 5Admission D-dimer is associated with subsequent cardiac rupture after acute myocardial infarction: a frequency-matched case-control study2026